1965 full-sized Pontiacs were completely restyled with more threads in sheet metal with a "Coke-bottle" profile and finishing fastback two-door hardtops. The wheelbase grew to 121 inches (3100 mm) on all models.

The new three-speed Turbo Hydramatic automatic transmission replaced the previous Roto Hydramatic unit on full-sized Pontiacs for 1965. "Turbo" There were three units of the speed torque converter similar in basic design to Torqueflite Chrysler and Ford Cruise-O-Matic transmission - a move that made the automatic torque converter transmission of universal design for helpless, and deliver the original Hydramatic fluid connection to history. While the "Turbo" channel continues to use the name Hydramatic, he shares none of his design with older programs. Turbo Hydramatic also adopted standardized "PRNDSL" shift pattern, which replaced the "PNDSLR" pattern long familiar to owners Hydramatic equipped Pontiacs, Oldsmobiles and Cadillacs.

389 and 421 cubic-inch V8s received a number of changes, including thinner block castings. The standard engine for model Catalina 389 two barrels capacity 256 hp (191 kW) with a base three-speed manual gearbox and 8.6 to 1 compression ratio or 290 horses with a Turbo Hydramatic transmission and above 10.5 to 1 compression. Fuel economy is regular 265 horsepower (198 kW) version of the 389 two barrels from 8.6 to 1 compression, which was burning regular gas was available for free version of turbo Hydramatic. Additional engines include four 389 barrel capacity of 325 horsepower (242 kW) turbocharged Hydramatic or 333 with a stick shift, Tri-Power 389 with capacity of 338 horses, four barrel capacity of 421 338 hp same (252 kW), 353 horses with Tri-Power or 421 HO with Tri-Power and 376 horsepower (280 kW).

2 +2 version changed from trim package all package for 1965 is similar to the average Pontiac GTO. The base engine with a 2 +2 is now 338-horsepower 421 four barrels from 353 hp (263 kW) Tri-Power or a 376-horsepower 421 HO with Tri-Power is available as an option.

In 1966, the full-sized Pontiacs received minor facelifting of the '65 body with a new lattice and rear treatment. Inside, the dashboard was revised with the salon. 2 +2 has been upgraded with the possibility of a complete model of the status and engine / transmission prices on all models Catalina remained the same in 1965, except for the elimination of 338-horsepower 389 Tri-Power option.

For 1967, Catalinas and other full-sized Pontiacs received heavy facelifting of the '65 body with a more rounded wasp-waisted body contours and finishing better fastback and concealed windshield wipers - the first in the industry. Replacing the 389 and 421 V8, in previous years were new 400 and 428 cubic-inch V8s built from the same V8 Pontiac design used since 1955. Standard engine Catalina had two barrel unit capacity of 265 horsepower (198 kW) with three-speed manual transmission or 290 horsepower (220 kW) Turbo-Hydramatic. 265 horsepower (198 kW) engine was available for free version with Turbo Hydramatic and differed from the standard 290 horsepower (220 kW) unit with regular gas as opposed to premium fuel. Additional engines include four 400 barrel capacity of 325 horsepower (242 kW), four barrel 428 with 360 hp (270 kW) or four barrel 428 HO power of 376 horsepower (280 kW). Options for Tri-Power engine was removed in 1967 in connection with the new GM corporate policy, which prohibits the use of several carbohydrates on all vehicles, except for Chevrolet Corvette. Front disc brakes and a stereo 8-track tape players were new additions to the list of options.

2 +2 has been proposed for the last time in 1967 as a hatchback coupe and convertible. 360-HP 428 is a standard and 428 HO is not mandatory. This model was rejected because of low sales since its introduction in 1964, performance car buyers overwhelmingly preferred smaller and lighter, intermediate, such as your own GTO Pontiac and new ponycar Firebird, which was introduced in 1967. 1967 Pontiac Catalina convertible was introduced in the Red Hot Chili Peppers video "Scar Tissue".

For 1968, Catalinas and other full-sized Pontiacs received minor facelifting of the '67 body with a new grille split beak nose and going back to the horizontal headlights, taillights and revised. Engine proposals were similar to 1967 with the revised horsepower ratings including 340, four barrel 400, 375, 428 and 390 four barrel, 428 HO.